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1

Will There Be a Cure for Ebola?

Cardile, Anthony P., Warren, Travis K., Martins, Karen A., Reisler, Ronald B., Bavari, Sina

Journal:

Annual Review of Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 248 KB

english, 2017

2

Identification of an antioxidant small-molecule with broad-spectrum antiviral activity

Rekha G. Panchal, St. Patrick Reid, Julie P. Tran, Alison A. Bergeron, Jay Wells, Krishna P. Kota, Javad Aman, Sina Bavari

Journal:

Antiviral Research

Année:

2012

Langue:

english

Fichier:

PDF, 791 KB

english, 2012

3

Analysis of Ebola virus and VLP release using an immunocapture assay

George Kallstrom, Kelly L. Warfield, Dana L. Swenson, Shannon Mort, Rekha G. Panchal, Gordon Ruthel, Sina Bavari, M. Javad Aman

Journal:

Journal of Virological Methods

Année:

2005

Langue:

english

Fichier:

PDF, 421 KB

english, 2005

4

HSPA5 is an essential host factor for Ebola virus infection

Patrick Reid, St., Shurtleff, Amy C., Costantino, Julie A., Tritsch, Sarah R., Retterer, Cary, Spurgers, Kevin B., Bavari, Sina

Journal:

Antiviral Research

Année:

2014

Langue:

english

Fichier:

PDF, 718 KB

english, 2014

5

Applications ofIn VivoImaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens

Bocan, Thomas M., Panchal, Rekha G., Bavari, Sina

Journal:

Molecular Imaging and Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2015

6

Vaccine adjuvant uses of poly-IC and derivatives

Martins, Karen AO, Bavari, Sina, Salazar, Andres M

Journal:

Expert Review of Vaccines

Année:

2015

Langue:

english

Fichier:

PDF, 521 KB

english, 2015

7

The Impact of Regulations, Safety Considerations and Physical Limitations on Research Progress at Maximum Biocontainment

Shurtleff, Amy, Garza, Nicole, Lackemeyer, Matthew, Carrion, Ricardo, Griffiths, Anthony, Patterson, Jean, Edwin, Samuel, Bavari, Sina

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

8

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Shurtleff, Amy, Biggins, Julia, Keeney, Ashley, Zumbrun, Elizabeth, Bloomfield, Holly, Kuehne, Ana, Audet, Jennifer, Alfson, Kendra, Griffiths, Anthony, Olinger, Gene, Bavari, Sina

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 292 KB

english, 2012

9

A Limited Structural Modification Results in a Significantly More Efficacious Diazachrysene-Based Filovirus Inhibitor

Selaković, Života, Opsenica, Dejan, Eaton, Brett, Retterer, Cary, Bavari, Sina, Burnett, James C., Šolaja, Bogdan A., Panchal, Rekha G.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 688 KB

english, 2012

10

High Content Image Based Analysis Identifies Cell Cycle Inhibitors as Regulators of Ebola Virus Infection

Kota, Krishna P., Benko, Jacqueline G., Mudhasani, Rajini, Retterer, Cary, Tran, Julie P., Bavari, Sina, Panchal, Rekha G.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 598 KB

english, 2012

11

Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections

Iversen, Patrick, Warren, Travis, Wells, Jay, Garza, Nicole, Mourich, Dan, Welch, Lisa, Panchal, Rekha, Bavari, Sina

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 422 KB

english, 2012

12

Correlates of Immunity to Filovirus Infection

Bradfute, Steven, Bavari, Sina

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 171 KB

english, 2011

13

Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014

Kuhn, Jens, Andersen, Kristian, Baize, Sylvain, Bào, Yīmíng, Bavari, Sina, Berthet, Nicolas, Blinkova, Olga, Brister, J., Clawson, Anna, Fair, Joseph, Gabriel, Martin, Garry, Robert, Gire, Stephen, Go

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 844 KB

english, 2014

14

Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names

Kuhn, Jens, Andersen, Kristian, Bào, Yīmíng, Bavari, Sina, Becker, Stephan, Bennett, Richard, Bergman, Nicholas, Blinkova, Olga, Bradfute, Steven, Brister, J., Bukreyev, Alexander, Chandran, Kartik, C

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 661 KB

english, 2014

15

Shedding Light on Filovirus Infection with High-Content Imaging

Pegoraro, Gianluca, Bavari, Sina, Panchal, Rekha G.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 440 KB

english, 2012

16

High degree of correlation between Ebola virus BSL-4 neutralization assays and pseudotyped VSV BSL-2 fluorescence reduction neutralization test

Konduru, Krishnamurthy, Shurtleff, Amy C., Bavari, Sina, Kaplan, Gerardo

Journal:

Journal of Virological Methods

Année:

2018

Langue:

english

Fichier:

PDF, 392 KB

english, 2018

17

Validation of the Filovirus Plaque Assay for Use in Preclinical Studies

Shurtleff, Amy, Bloomfield, Holly, Mort, Shannon, Orr, Steven, Audet, Brian, Whitaker, Thomas, Richards, Michelle, Bavari, Sina

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2016

18

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges)

Dye, John, Warfield, Kelly, Wells, Jay, Unfer, Robert, Shulenin, Sergey, Vu, Hong, Nichols, Donald, Aman, M., Bavari, Sina

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.28 MB

english, 2016

19

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses

Bào, Yīmíng, Amarasinghe, Gaya, Basler, Christopher, Bavari, Sina, Bukreyev, Alexander, Chandran, Kartik, Dolnik, Olga, Dye, John, Ebihara, Hideki, Formenty, Pierre, Hewson, Roger, Kobinger, Gary, Ler

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 837 KB

english, 2017

20

Ebola Virus Causes Intestinal Tract Architectural Disruption and Bacterial Invasion in Non-Human Primates

Reisler, Ronald, Zeng, Xiankun, Schellhase, Christopher, Bearss, Jeremy, Warren, Travis, Trefry, John, Christopher, George, Kortepeter, Mark, Bavari, Sina, Cardile, Anthony

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.96 MB

english, 2018

21

Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein

Morwitzer, M. Jane, Tritsch, Sarah R., Cazares, Lisa H., Ward, Michael D., Nuss, Jonathan E., Bavari, Sina, Reid, St Patrick

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2019

22

Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein

Morwitzer, M. Jane, Tritsch, Sarah R., Cazares, Lisa H., Ward, Michael D., Nuss, Jonathan E., Bavari, Sina, Reid, St Patrick

Journal:

Année:

2019

Fichier:

PDF, 2.47 MB

2019

23

ChemInform Abstract: Synthesis and Biological Evaluation of Inhibitors of Botulinum Neurotoxin Metalloprotease.

Chenbo Wang, Julia Widom, Filip Petronijevic, James C. Burnett, Jonathan E. Nuss, Sina Bavari, Rick Gussio, Peter Wipf

Journal:

Année:

2009

Fichier:

PDF, 33 KB

2009

24

Three-Dimensional Database Mining Identifies a Unique Chemotype that Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors in a Three-Zone Pharmacophore

Ann R. Hermone, James C. Burnett, Jonathan E. Nuss, Lyal E. Tressler, Tam L. Nguyen, Bogdan A. Šolaja, Jonathan L. Vennerstrom, James J. Schmidt, Peter Wipf, Sina Bavari, Rick Gussio

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 726 KB

english, 2008

25

Toward RNA interference-based therapy for filovirus infections

Kevin B. Spurgers, Lynn S. Silvestri, Kelly L. Warfield, Sina Bavari

Journal:

Drug Development Research

Année:

2009

Langue:

english

Fichier:

PDF, 142 KB

english, 2009

26

A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of α chain, β chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens

Xiaojie Zhu, Sina Bavari, Robert Ulrich, Scheherazade Sadegh-Nasseri, Soldano Ferrone, Louise McHugh, Michael Mage

Journal:

European Journal of Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1997

27

Protective effects of niacinamide in staphylococcal enterotoxin-B-induced toxicity

Ross D. LeClaire, Wayne Kell, Sina Bavari, Theresa J. Smith, Robert E. Hunt

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.19 MB

english, 1996

28

Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding

James C. Burnett, James J. Schmidt, Connor F. McGrath, Tam L. Nguyen, Ann R. Hermone, Rekha G. Panchal, Jonathan L. Vennerstrom, Krishna Kodukula, Daniel W. Zaharevitz, Rick Gussio, Sina Bavari

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 919 KB

english, 2005

29

Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR

Timothy J. Opperman, John D. Williams, Chad Houseweart, Rekha G. Panchal, Sina Bavari, Norton P. Peet, Donald T. Moir, Terry L. Bowlin

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 488 KB

english, 2010

30

Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-Induced Pathogenesis

Rekha G. Panchal, Gordon Ruthel, Katherine C. Brittingham, Douglas Lane, Tara A. Kenny, Rick Gussio, John S. Lazo, Sina Bavari

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2007

31

A theoretical study of anthrax lethal factor inhibition by a set of novel carbamimidolyl-aryl-vinyl-carboxamidines: A possible mechanism involving zinc-ligation by amidine

Tam Luong Nguyen, Rekha G. Panchal, Igor A. Topol, Douglas Lane, Tara Kenny, James C. Burnett, Ann R. Hermone, Connor McGrath, Stanley K. Burt, Rick Gussio, Sina Bavari

Journal:

Journal of Molecular Structure: THEOCHEM

Année:

2007

Langue:

english

Fichier:

PDF, 497 KB

english, 2007

32

Generation of Marburg virus-like particles by co-expression of glycoprotein and matrix protein

Dana L. Swenson, Kelly L. Warfield, Kathleen Kuehl, Thomas Larsen, Michael C. Hevey, Alan Schmaljohn, Sina Bavari, M.Javad Aman

Journal:

FEMS Immunology & Medical Microbiology

Année:

2004

Langue:

english

Fichier:

PDF, 258 KB

english, 2004

33

Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B

Brian Drozdowski, Yuhong Zhou, Brad Kline, Jared Spidel, Yin Yin Chan, Earl Albone, Howard Turchin, Qimin Chao, Marianne Henry, Jacqueline Balogach, Eric Routhier, Sina Bavari, Nicholas C Nicolaides,

Journal:

Journal of Immune Based Therapies and Vaccines

Année:

2010

Langue:

english

Fichier:

PDF, 653 KB

english, 2010

34

Treatment of highly pathogenic filovirus infections using advanced antisense technology

Travis Warren, Kelly Warfield, Jay Wells, Dana Swenson, Candace Lovejoy, Patrick Iversen, Sina Bavari

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 127 KB

english, 2010

35

Erratum to: “Molecular mechanisms of filovirus cellular trafficking” [Microbes Infect. 5 (2003) 639–649]

M.Javad Aman, Catharine M. Bosio, Rekha G. Panchal, James C. Burnett, Alan Schmaljohn, Sina Bavari

Journal:

Microbes and Infection

Année:

2003

Langue:

english

Fichier:

PDF, 91 KB

english, 2003

36

NKp30-dependent cytolysis of filovirus-infected human dendritic cells

Claudette L. Fuller, Gordon Ruthel, Kelly L. Warfield, Dana L. Swenson, Catharine M. Bosio, M. Javad Aman, Sina Bavari

Journal:

Cellular Microbiology

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

37

Humanized mice as a preclinical tool for infectious disease and biomedical research

Leonard D. Shultz, Michael A. Brehm, Sina Bavari, Dale L. Greiner

Journal:

Annals of the New York Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 607 KB

english, 2011

38

The evolving field of biodefence: therapeutic developments and diagnostics

Burnett, James C., Henchal, Erik A., Schmaljohn, Alan L., Bavari, Sina

Journal:

Nature Reviews Drug Discovery

Année:

2005

Langue:

english

Fichier:

PDF, 389 KB

english, 2005

39

Staphylococcal enterotoxins A and B share a common structural motif for binding class II major histocompatibility complex molecules

Ulrich, Robert G., Bavari, Sina, Olson, Mark A.

Journal:

Natural Structural Biology

Année:

1995

Fichier:

PDF, 1011 KB

1995

40

Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses

Radoshitzky, Sheli R, Kuhn, Jens H, de Kok-Mercado, Fabian, Jahrling, Peter B, Bavari, Sina

Journal:

Expert Opinion on Drug Discovery

Année:

2012

Langue:

english

Fichier:

PDF, 558 KB

english, 2012

41

Divergence of Human and Nonhuman Primate Lymphocyte Responses to Bacterial Superantigens

Sina Bavari, Robert E. Hunt, Robert G. Ulrich

Journal:

Clinical Immunology and Immunopathology

Année:

1995

Fichier:

PDF, 435 KB

1995

42

Phosphorodiamidate Morpholino Oligomer—Mediated Inhibition of Influenza A Virus in Mice

Thomas Voss, Kelly Warfield, Rebecca Brocato, Joseph Barbercheck, Bryan Kaplin, David Stein, Sina Bavari, Patrick Iversen

Journal:

Antiviral Research

Année:

2007

Langue:

english

Fichier:

PDF, 65 KB

english, 2007

43

Oligonucleotide antiviral therapeutics: Antisense and RNA interference for highly pathogenic RNA viruses

Kevin B. Spurgers, C. Matthew Sharkey, Kelly L. Warfield, Sina Bavari

Journal:

Antiviral Research

Année:

2008

Langue:

english

Fichier:

PDF, 364 KB

english, 2008

44

Identification of a Small-molecule Antiviral with Broad-spectrum Application to Multiple, Lethal Virus Types

Abdul Yunus, Travis Warren, Kelly Warfield, Sven Enterlein, Shaojing Chang, Hanwen Mao, Javad Aman, Sina Bavari, Michael Goldblatt, Michael Kinch

Journal:

Antiviral Research

Année:

2009

Langue:

english

Fichier:

PDF, 87 KB

english, 2009

45

Development of a broad-spectrum antiviral with activity against Ebola virus

M. Javad Aman, Michael S. Kinch, Kelly Warfield, Travis Warren, Abdul Yunus, Sven Enterlein, Eric Stavale, Peifang Wang, Shaojing Chang, Qingsong Tang, Kevin Porter, Michael Goldblatt, Sina Bavari

Journal:

Antiviral Research

Année:

2009

Langue:

english

Fichier:

PDF, 830 KB

english, 2009

46

The Discovery and Efficacy of a Small Molecule Inhibitor of Ebola Capsid Assembly in an Animal Model

Jean Francis, Warren Kalina, Travis Warren, Katie Edwards, I-ting Jaing, A. Pia Abola, Abhar Nissar, Anatoliy Kitaygorodskyy, Clarence R. Hurt, Sina Bavari, William Hansen, Vishwanath R. Lingappa

Journal:

Antiviral Research

Année:

2010

Langue:

english

Fichier:

PDF, 90 KB

english, 2010

47

Crimean-Congo hemorrhagic fever: Current and future prospects of vaccines and therapies

Maryam Keshtkar-Jahromi, Jens H. Kuhn, Iva Christova, Steven B. Bradfute, Peter B. Jahrling, Sina Bavari

Journal:

Antiviral Research

Année:

2011

Langue:

english

Fichier:

PDF, 178 KB

english, 2011

48

Advanced morpholino oligomers: A novel approach to antiviral therapy

Travis K. Warren, Amy C. Shurtleff, Sina Bavari

Journal:

Antiviral Research

Année:

2012

Langue:

english

Fichier:

PDF, 726 KB

english, 2012

49

Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors

Bing Li, Steven C. Cardinale, Michelle M. Butler, Ramdas Pai, Jonathan E. Nuss, Norton P. Peet, Sina Bavari, Terry L. Bowlin

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2011

50

The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease

Igor Opsenica, Vuk Filipovic, Jon E. Nuss, Laura M. Gomba, Dejan Opsenica, James C. Burnett, Rick Gussio, Bogdan A. Solaja, Sina Bavari

Journal:

European Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 259 KB

english, 2012